2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

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Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-105154
    Proxodolol free base 152289-58-2 98%
    Proxodolol free base is a β-adrenergic receptor blocker. Proxodolol free base can be used for the study of arterial hypertension.
    Proxodolol free base
  • HY-105205
    Terlakiren 119625-78-4 98%
    Terlakiren (CP-80,794) is an orally active inhibitor of renin. Terlakiren inhibits the efficacy of human renin with an IC50 value of 0.7 nM. Terlakiren has potential applications in hypertension.
    Terlakiren
  • HY-105209
    Pirsidomine 132722-74-8 98%
    Pirsidomine is a nitric oxide donor. Pirsidomine is a sydnonimine compound. Pirsidomine can transform into a nitric oxide-releasing metabolite in vivo. Pirsidomine prevents occlusion-induced increase in flow in the non-occluded circumflex coronary artery and significantly reduces the blood flow in non-ischemic areas in myocardial infarction dog model. Pirsidomine can be studied in research on cardiovascular diseases.
    Pirsidomine
  • HY-105225
    Glaspimod 134143-28-5 98%
    Glaspimod is a haemoregulatory peptide.
    Glaspimod
  • HY-105227
    FK 838 131185-37-0 98%
    FK 838 is an adenosine subtype-1 receptor antagonist with potent diuretic activity. FK 838 can be used for the research of cardiovascular disease, such as hypertension .
    FK 838
  • HY-105240
    Delparantag 872454-31-4 98%
    Delparantag (PMX-60056) is a salicylamide derivative and an effective unfractionated heparin (UFH) and low molecular weight heparin (LMWH) reversing agent. Delparantag shows ability to neutralize the anticoagulation and bleeding effects of UFH and LMWH.
    Delparantag
  • HY-105261
    Idrapril 127420-24-0 98%
    Idrapril is an ACE inhibitor. Idrapril can be studied in research on acute myocardial ischaemia and reperfusion.
    Idrapril
  • HY-105265
    Rolafagrel 89781-55-5 98%
    Rolafagrel is an inhibitor of thromboxane synthase. Rolafagrel can be studied in cardiovascular research.
    Rolafagrel
  • HY-105266
    Zabicipril 83059-56-7 98%
    Zabicipril is an orally active angiotensin-converting enzyme (ACE) inhibitor. Zabicipril can be used for the study of blood pressure and peripheral arterial insufficiency.
    Zabicipril
  • HY-105298
    CR 3834 868741-81-5 98%
    CR 3834 is a angiotensin-AT1 antagonist. CR 3834 can be used for the research of cardiovascular disease.
    CR 3834
  • HY-105319
    CGS-30440 169319-62-4 98%
    CGS-30440 is a potent and orally active dual inhibitor of neutral endopeptidase (NEP) and angiotensin-converting enzyme (ACE). CGS-30440 exhibit antihypertensive and natriuretic effects. CGS-30440 also shows protective effect for chronic renal failure. CGS-30440 can be used for the research of cardiovascular disease, such as hypertension.
    CGS-30440
  • HY-105323
    YM758 phosphate 312752-86-6 98%
    YM758 phosphate is a "funny" If current channel (If channel) inhibitor.
    YM758 phosphate
  • HY-105341
    UK 343664 215297-27-1 98%
    UK 343664 is a potent, orally active and selective PDE5 inhibitor. UK 343664 partially reverses Thromboxane-induced pulmonary hypertension.
    UK 343664
  • HY-105362
    PD 155080 162412-71-7 98%
    PD 155080 is a selective endothelin A receptor (ETA receptor) antagonist. PD 155080 reduces coronary resistance in the isolated rat heart model. PD 155080 improves myocardial systolic function and diastolic function in the ischemia/reperfusion model. PD 155080 can be used for the study of cardiovascular diseases.
    PD 155080
  • HY-105363
    RGH-1962 218907-16-5 98%
    RGH-1962 is an orally active antithrombotic agent. RGH-1962 prevents endotoxin-induced decreases in fibrinogen level and platelet count, reduces the level of fibrin degradation products and inhibits the endotoxin-induced enhancement of fibrinolytic activity in a rabbit model of endotoxin-induced disseminated intravascular coagulation. RGH-1962 can be used for the study of thrombotic diseases.
    RGH-1962
  • HY-105364
    RGH-1875 hydriodide 214272-33-0 98%
    RGH-1875 (GYKI 39521) hydriodide is the hydriodide of RGH-1875. RGH-1875 is an orally active antithrombotic agent. RGH-1875 prevents endotoxin-induced decreases in fibrinogen level and platelet count, reduces the level of fibrin degradation products and inhibits the endotoxin-induced enhancement of fibrinolytic activity in a rabbit model of endotoxin-induced disseminated intravascular coagulation. RGH-1875 can be used for the study of thrombotic diseases.
    RGH-1875 hydriodide
  • HY-105383
    L 373890 187162-33-0 98%
    L 373890 is a selective pyridinone acetamide thrombin inhibitor with a Ki of 0.5 nM. L 373890 shows highly selectivity for thrombin over trypsin (Ki of 570 nM), serine proteases plasmin, tPA, activated protein C, plasma kallikrein and chymotrypsin. L 373890 can be used for thrombosis research.
    L 373890
  • HY-105390
    Renin-IN-4 85139-12-4 98%
    Renin-IN-4 is a Renin inhibitor. Renin-IN-4 can be used for the research of cardiovascular disease.
    Renin-IN-4
  • HY-105402
    T 162559 339532-12-6 98%
    T 162559 is a potent and selective inhibitor of the Na+/H+ exchanger isoform NHE1 with IC50 values of 0.96 nM. T 162559 does not affect Na+/HCO3- cotransport and Na+/Ca2+ exchange. T 162559 can be used for the research of cardiovascular disease.
    T 162559
  • HY-105418
    WIN-63291 144967-96-4 98%
    WIN-63291 is a selective and orally active phosphodiesterase (PDE) III inhibitor. WIN-63291 can be used for the research of cardiovascular disease.
    WIN-63291
Cat. No. Product Name / Synonyms Application Reactivity